货号： 680664
别名： RPTOR; ARaptor (phospho S792); Raptor (phospho Ser792); p-Raptor (Ser792); p150 target of rapamycin (TOR) scaffold protein containing WD repeats; P150 target of rapamycin (TOR)-scaffold protein; Regulatory Associated Protein of mTOR; KIAA1303; RPTOR_HUMAN; Regulatory-associated protein of mTOR; p150 target of rapamycin (TOR)-scaffold protein.
应用： IHC-F,IHC-P,ICC/IF,ELISA
反应种属： Human,Mouse
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-Raptor (Ser792) Rabbit pAb
  • Gene ID
    57521
  • SwissProt ID
    Q8N122
  • Gene Name
    RPTOR
  • Alternative Names
    RPTOR; ARaptor (phospho S792); Raptor (phospho Ser792); p-Raptor (Ser792); p150 target of rapamycin (TOR) scaffold protein containing WD repeats; P150 target of rapamycin (TOR)-scaffold protein; Regulatory Associated Protein of mTOR; KIAA1303; RPTOR_HUMAN; Regulatory-associated protein of mTOR; p150 target of rapamycin (TOR)-scaffold protein.
  • Background
    The regulatory associated protein of mTOR (Raptor) was identified as an mTOR binding partner that mediates mTOR signaling to downstream targets. Raptor binds to mTOR substrates, including 4E-BP1 and p70 S6 kinase, through their TOR signaling (TOS) motifs and is required for mTOR-mediated phosphorylation of these substrates. Binding of the FKBP12-rapamycin complex to mTOR inhibits the mTOR-raptor interaction, suggesting a mechanism for rapamycin's specific inhibition of mTOR signaling. This mTOR-raptor interaction and its regulation by nutrients and/or rapamycin is dependent on a protein called GβL.
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse
  • Application
    IHC-F,IHC-P,ICC/IF,ELISA
  • Dilution Ratio
    IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/5000-1/10000
  • Molecular Weight
    Calculated MW: 140kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    KLH conjugated Synthesised phosphopeptide derived from human Raptor around the phosphorylation site of Ser792
  • Purification
    affinity purified by Protein A
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    Liquid
  • Buffer System
    0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
  • Storage
    Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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