货号： 680345
别名： IRE1a; Endoplasmic reticulum (ER) to nucleus signalling 1; Endoplasmic reticulum to nucleus signaling 1; Endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signaling 1; ERN 1; ERN1; ERN1_HUMAN; hIRE 1p; hIRE1p; Inositol requiring 1; Inositol requiring protein 1; Inositol-requiring protein 1; IRE-1; IRE 1; IRE 1a; IRE 1P; Ire1 alpha; Ire1-alpha; Ire1alpha; IRE1P; MGC163277; Protein kinase/endoribonuclease; Serine/threonine protein kinase/endoribonuclease IRE1.
应用： WB,IHC-F,IHC-P,ICC/IF,FC,ELISA
反应种属： Human,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    IRE1 Rabbit pAb
  • Gene ID
    10595
  • SwissProt ID
    O75460
  • Gene Name
    ERN1
  • Alternative Names
    IRE1a; Endoplasmic reticulum (ER) to nucleus signalling 1; Endoplasmic reticulum to nucleus signaling 1; Endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signaling 1; ERN 1; ERN1; ERN1_HUMAN; hIRE 1p; hIRE1p; Inositol requiring 1; Inositol requiring protein 1; Inositol-requiring protein 1; IRE-1; IRE 1; IRE 1a; IRE 1P; Ire1 alpha; Ire1-alpha; Ire1alpha; IRE1P; MGC163277; Protein kinase/endoribonuclease; Serine/threonine protein kinase/endoribonuclease IRE1.
  • Background
    Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
  • Research Field
    Signal Transduction
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Rat
  • Application
    WB,IHC-F,IHC-P,ICC/IF,FC,ELISA
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/5000-1/10000
  • Molecular Weight
    Calculated MW: 105kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    KLH conjugated synthetic peptide derived from human IRE1a
  • Purification
    affinity purified by Protein A
  • Conjugation
    Unconjugated
  • Modification
    Unmodified
  • Form
    Liquid
  • Buffer System
    0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
  • Storage
    Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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