产品详情
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Product Name
IRS1 Rabbit pAb
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Gene ID
3667
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SwissProt ID
P35568
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Gene Name
IRS1
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Alternative Names
IRS1_HUMAN; Insulin receptor substrate 1; IRS-1; IRS 1;
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Background
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .
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Research Field
Tags & Cell Markers
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Mouse,Rat
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Application
IHC-F,IHC-P,ICC/IF
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Dilution Ratio
IHC: 1/50-1/100 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 132kDa
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
KLH conjugated synthetic peptide derived from human IRS1
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Purification
affinity purified by Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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