货号： 680528
别名： B-Raf (phospho Ser365); B-Raf (phospho S365); B-Raf (phospho-Ser365); BRAF_HUMAN; Serine/threonine-protein kinase B-raf; EC:2.7.11.1; BRAF1; RAFB1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1; B-Raf proto-oncogene, serine/threonine kinase; NS7; B-raf; B-RAF1; BRAF-1; 94 kDa B raf protein;
应用： IHC-F,IHC-P,ICC/IF,ELISA
反应种属： Human,Mouse,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-BRAF (Ser365) Rabbit pAb
  • Gene ID
    673
  • SwissProt ID
    P15056
  • Gene Name
    BRAF
  • Alternative Names
    B-Raf (phospho Ser365); B-Raf (phospho S365); B-Raf (phospho-Ser365); BRAF_HUMAN; Serine/threonine-protein kinase B-raf; EC:2.7.11.1; BRAF1; RAFB1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1; B-Raf proto-oncogene, serine/threonine kinase; NS7; B-raf; B-RAF1; BRAF-1; 94 kDa B raf protein;
  • Background
    Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations.
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Application
    IHC-F,IHC-P,ICC/IF,ELISA
  • Dilution Ratio
    IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/5000-1/10000
  • Molecular Weight
    Calculated MW: 84kDa
  • Clonality
    Polyclonal Antibody
  • Clonality No.
    -
  • Isotype
    IgG
  • Immunogen
    KLH conjugated Synthesised phosphopeptide derived from human BRAF around the phosphorylation site of Ser365
  • Purification
    affinity purified by Protein A
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    Liquid
  • Buffer System
    0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
  • Storage
    Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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