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Product Name
Phospho-AMPK1 (Ser485) Rabbit pAb
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Gene ID
5562
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SwissProt ID
Q13131
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Gene Name
AAPK1
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Alternative Names
5'-AMP-activated protein kinase; catalytic alpha-1 chain; AAPK1; AMPK alpha-1 chain; AMPK-alpha1; EC 2.7.11.1; HMG-CoA redustase kinase; PRKAA1; acetyl-CoA carboxylase kinase; hormone-sensitive lipase kinase; kinase AMPK-alpha1; 5'-AMP-activated protein k
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Background
Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357, PubMed:24563466, PubMed:37821951).
In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation (PubMed:17307971, PubMed:17712357).
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/3000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 62 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human AMPK1 around the phosphorylation site of Ser485.
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.