-
Product Name
Phospho-APLP2 (Tyr755) Rabbit pAb
-
Gene ID
334
-
SwissProt ID
Q06481
-
Gene Name
APLP2
-
Alternative Names
Amyloid protein homolog; Amyloid-like protein 2 precursor; APLP2; APP2; APPH; APPL2; CDEBP; CDEI-box binding protein
-
Background
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).
-
Research Field
Neuroscience
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
IHC-P
-
Dilution Ratio
IHC: 1/50-1/100
-
Molecular Weight
Calculated MW: 86 kDa
-
Clonality
Polyclonal Antibody
-
Isotype
IgG
-
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human APLP2 around the phosphorylation site of tyrosine 755 (P-T-YP-K-Y).
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Phosphorylated
-
Form
liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.