货号： 690042
别名： ataxia telangiectasia and Rad3-related protein; EC 2.7.11.1; FRAP-related protein; FRP1; kinase ATR; protein kinase ATR
应用： IHC-P
反应种属： Human
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-ATR (Ser428) Rabbit pAb
  • Gene ID
    545
  • SwissProt ID
    Q13535
  • Gene Name
    ATR
  • Alternative Names
    ataxia telangiectasia and Rad3-related protein; EC 2.7.11.1; FRAP-related protein; FRP1; kinase ATR; protein kinase ATR
  • Background
    Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor (PubMed:10597277, PubMed:10608806, PubMed:10859164, PubMed:11721054, PubMed:12791985, PubMed:12814551, PubMed:14657349, PubMed:14729973, PubMed:14742437, PubMed:15210935, PubMed:15496423, PubMed:16260606, PubMed:21144835, PubMed:21777809, PubMed:23273981, PubMed:25083873, PubMed:27723717, PubMed:27723720, PubMed:30139873, PubMed:33848395, PubMed:37788673, PubMed:37832547, PubMed:9427750, PubMed:9636169).
  • Research Field
    Epigenetics and Nuclear Signaling
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human
  • Application
    IHC-P
  • Dilution Ratio
    IHC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 301 kDa
  • Clonality
    Polyclonal Antibody
  • Isotype
    IgG
  • Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human ATR around the phosphorylation site of serine 428 (G-I-SP-P-K).
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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