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Product Name
Phospho-Myc (Thr358) Rabbit pAb
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Gene ID
4609
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SwissProt ID
P01106
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Gene Name
MYC
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Alternative Names
Myc proto-oncogene protein, c-myc
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Background
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029).
Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029).
Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029).
Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity).
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
IHC-P,IP
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Dilution Ratio
IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 48 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human Myc around the phosphorylation site of Thr358
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.