货号： 690076
别名： Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, EC 3.4.22.-, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
应用： WB,IHC-P
反应种属： Human,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-Caspase 8 (Ser347) Rabbit pAb
  • Gene ID
    841
  • SwissProt ID
    Q14790
  • Gene Name
    CASP8
  • Alternative Names
    Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, EC 3.4.22.-, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
  • Background
    Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood (PubMed:23516580, PubMed:35338844, PubMed:35446120, PubMed:8681376, PubMed:8681377, PubMed:8962078, PubMed:9006941, PubMed:9184224).
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Rat
  • Application
    WB,IHC-P
  • Dilution Ratio
    WB: 1/500-1/3000 IHC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 55 kDa
  • Clonality
    Polyclonal Antibody
  • Isotype
    IgG
  • Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human Caspase 8 around the phosphorylation site of serine 347 (C-P-SP-L-A)
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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