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Product Name
Phospho-NMDAR1 (Ser890) Rabbit pAb
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Gene ID
2902
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SwissProt ID
Q05586
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Gene Name
GRIN1
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Alternative Names
GLURZ1, GRIN1, Glutamate [NMDA] receptor subunit zeta 1 precursor, N-methyl-D-aspartate receptor, NMD-R1, NMDZ1, NMZ1, NR1
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Background
Component of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg2+ (PubMed:21376300, PubMed:26875626, PubMed:26919761, PubMed:28126851, PubMed:28228639, PubMed:36959261, PubMed:7679115, PubMed:7681588, PubMed:7685113).
NMDARs participate in synaptic plasticity for learning and memory formation by contributing to the long-term potentiation (LTP) (PubMed:26875626).
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
IHC-P,ICC/IF
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Dilution Ratio
IHC: 1/50-1/100 ICC/IF: 1/100-1/500
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Molecular Weight
Calculated MW: 105 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human NMDAR1 around the phosphorylation site of serine 890 (A-S-SP-F-K).
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.