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Product Name
Phospho-CDC25C (Thr48) Rabbit pAb
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Gene ID
995
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SwissProt ID
P30307
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Gene Name
CDC25A
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Alternative Names
CDC25M1, Dual specificity phosphatase Cdc25C, EC 3.1.3.48, M-phase inducer phosphatase 3, MPIP3
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Background
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle (PubMed:8119945).
When phosphorylated, highly effective in activating G2 cells into prophase (PubMed:8119945).
Directly dephosphorylates CDK1 and activates its kinase activity (PubMed:8119945).
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/3000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 53 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human CDC25C around the phosphorylation site of Thr48
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.