货号： 690358
别名： Early response protein NAK1, GFRP, GFRP1, HMR, N10, N10 nuclear protein, NAK1, NGFI-B, NGFIB, NR4A1, Nuclear hormone receptor NUR/77, Orphan nuclear receptor HMR, TR3 orphan receptor
应用： IHC-P
反应种属： Human,Mouse,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-Nuclear Receptor NR4A1 (Ser351) Rabbit pAb
  • Gene ID
    3164
  • SwissProt ID
    P22736
  • Gene Name
    NR4A1
  • Alternative Names
    Early response protein NAK1, GFRP, GFRP1, HMR, N10, N10 nuclear protein, NAK1, NGFI-B, NGFIB, NR4A1, Nuclear hormone receptor NUR/77, Orphan nuclear receptor HMR, TR3 orphan receptor
  • Background
    Orphan nuclear receptor. Binds the NGFI-B response element (NBRE) 5'-AAAGGTCA-3' (PubMed:18690216, PubMed:8121493, PubMed:9315652). Binds 9-cis-retinoic acid outside of its ligand-binding (NR LBD) domain (PubMed:18690216). Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation (PubMed:22983157). Regulates the inflammatory response in macrophages by regulating metabolic adaptations during inflammation, including repressing the transcription of genes involved in the citric acid cycle (TCA) (By similarity).
  • Research Field
    Cell Biology
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Application
    IHC-P
  • Dilution Ratio
    IHC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 64 kDa
  • Clonality
    Polyclonal Antibody
  • Isotype
    IgG
  • Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human Nuclear Receptor NR4A1 around the phosphorylation site of serine 351 (L-P-SP-K-P).
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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