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Product Name
Phospho-p130 Cas (Tyr410) Rabbit pAb
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Gene ID
9564
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SwissProt ID
P56945
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Gene Name
BCAR1
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Alternative Names
BCAR1, Breast cancer anti-estrogen resistance 1, CRK-ASSOCIATED SUBSTRATE, CRKAS
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Background
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion (PubMed:12432078, PubMed:12832404).
Implicated in induction of cell migration and cell branching (PubMed:12432078, PubMed:12832404, PubMed:17038317).
Involved in the BCAR3-mediated inhibition of TGFB signaling (By similarity).
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/3000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 93 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human p130 Cas around the phosphorylation site of tyrosine 410 (G-V-YP-A-V).
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.