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Product Name
Phospho-p21 Cip1 (Thr145) Rabbit pAb
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Gene ID
1026
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SwissProt ID
P38936
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Gene Name
CDKN1A
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Alternative Names
CAP20; CDK-interacting protein 1; CDKN1; CDKN1A; CDN1A; CIP1; Cyclin-dependent kinase inhibitor 1; MDA-6; MDA6; Melanoma differentiation associated protein; Melanoma differentiation associated protein 6; p21; PIC1; SDI1; WAF1
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Background
Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest (PubMed:9106657).
Involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Also involved in p53-independent DNA damage-induced G2 arrest mediated by CREB3L1 in astrocytes and osteoblasts (By similarity).
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/3000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 17 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human p21 Cip1 around the phosphorylation site of Thr145
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.