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Product Name
Phospho-CK-1α (Tyr294) Rabbit pAb
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Gene ID
1452/122011
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SwissProt ID
P48729/Q8N752
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Gene Name
CSNK1A1
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Alternative Names
Casein kinase I, alpha isoform; CK1-alpha; CKI-alpha; CSNK1A1; EC 2.7.11.1; KC1A; kinase CK1-alpha
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Background
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (PubMed:11955436, PubMed:1409656, PubMed:18305108, PubMed:23902688).
It can phosphorylate a large number of proteins (PubMed:11955436, PubMed:1409656, PubMed:18305108, PubMed:23902688).
Participates in Wnt signaling (PubMed:11955436).
Phosphorylates CTNNB1 at 'Ser-45' (PubMed:11955436).
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/3000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 38 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human CK-1α around the phosphorylation site of tyrosine 294 (Y-D-YP-T-F).
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.