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Product Name
Phospho-PLCB3 (Ser1105) Rabbit pAb
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Gene ID
5331
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SwissProt ID
Q01970
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Gene Name
PLCB3
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Alternative Names
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3,EC 3.1.4.11, Phosphoinositide phospholipase C,Phospholipase C-beta-3,PLC-beta-3,PLCB3
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Background
Catalyzes the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) (PubMed:20966218, PubMed:29122926, PubMed:37991948, PubMed:9188725).
Key transducer of G protein-coupled receptor signaling: activated by G(q)/G11 G alpha proteins downstream of G protein-coupled receptors activation (PubMed:20966218, PubMed:37991948).
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/3000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 138 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human PLC-β around the phosphorylation site of serine 1105 (N-N-SP-I-S).
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.