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Product Name
Phospho-Elk1 (Thr417) Rabbit pAb
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Gene ID
2002
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SwissProt ID
P19419
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Gene Name
ELK1
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Alternative Names
ELK1; ETS-domain protein ELK-1; ETS-domain protein Elk-1
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Background
Transcription factor that binds to purine-rich DNA sequences (PubMed:10799319, PubMed:7889942).
Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2 (PubMed:1630903).
Induces target gene transcription upon JNK and MAPK-signaling pathways stimulation (PubMed:7889942).
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
IHC-P,IP
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Dilution Ratio
IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 44 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human Elk1 around the phosphorylation site of Thr417
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.