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Product Name
Phospho-FHIT (Tyr114) Rabbit pAb
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Gene ID
2272
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SwissProt ID
P49789
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Gene Name
FHIT
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Alternative Names
AP3A hydrolase; AP3AASE; Bis(5'-adenosyl)-triphosphatase; Bis(5'-adenosyl)-triphosphatease; Dinucleosidetriphosphatase; EC 3.6.1.29; Fragile histidine triad protein
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Background
Possesses dinucleoside triphosphate hydrolase activity (PubMed:12574506, PubMed:15182206, PubMed:8794732, PubMed:9323207, PubMed:9543008, PubMed:9576908).
Cleaves P1-P3-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP (PubMed:12574506, PubMed:15182206, PubMed:8794732, PubMed:9323207, PubMed:9543008, PubMed:9576908).
Can also hydrolyze P1-P4-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP (PubMed:8794732).
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
IHC-P
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Dilution Ratio
IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 16 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human FHIT around the phosphorylation site of tyrosine 114 (S-I-YP-E-E).
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.