货号： 690451
别名： HBP, HRS binding protein, Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2, Signal transducing adaptor molecule 2A, Signal transducing adaptor molecule 2B
应用： WB
反应种属： Human,Mouse
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-STAM2 (Tyr192) Rabbit pAb
  • Gene ID
    8986
  • SwissProt ID
    O75886
  • Gene Name
    STAM2
  • Alternative Names
    HBP, HRS binding protein, Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2, Signal transducing adaptor molecule 2A, Signal transducing adaptor molecule 2B
  • Background
    Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as a sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).
  • Research Field
    Signal Transduction
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse
  • Application
    WB
  • Dilution Ratio
    WB: 1/500-1/3000
  • Molecular Weight
    Calculated MW: 58 kDa
  • Clonality
    Polyclonal Antibody
  • Isotype
    IgG
  • Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human STAM2 around the phosphorylation site of tyrosine 192 (S-L-YP-P-S).
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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