货号： 690459
别名： DCHT; EC 2.7.11.1; Serine/threonine-protein kinase 39; SPAK; Ste-20 related kinase; STE20/SPS1-related proline-alanine rich protein kinase; STK39
应用： IHC-P
反应种属： Human,Mouse,Rat
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-STK39 (Ser325) Rabbit pAb
  • Gene ID
    27347
  • SwissProt ID
    Q9UEW8
  • Gene Name
    STK39
  • Alternative Names
    DCHT; EC 2.7.11.1; Serine/threonine-protein kinase 39; SPAK; Ste-20 related kinase; STE20/SPS1-related proline-alanine rich protein kinase; STK39
  • Background
    Effector serine/threonine-protein kinase component of the WNK-SPAK/OSR1 kinase cascade, which is involved in various processes, such as ion transport, response to hypertonic stress and blood pressure (PubMed:16669787, PubMed:18270262, PubMed:21321328, PubMed:34289367). Specifically recognizes and binds proteins with a RFXV motif (PubMed:16669787, PubMed:21321328). Acts downstream of WNK kinases (WNK1, WNK2, WNK3 or WNK4): following activation by WNK kinases, catalyzes phosphorylation of ion cotransporters, such as SLC12A1/NKCC2, SLC12A2/NKCC1, SLC12A3/NCC, SLC12A5/KCC2 or SLC12A6/KCC3, regulating their activity (PubMed:21321328).
  • Research Field
    Signal Transduction
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Application
    IHC-P
  • Dilution Ratio
    IHC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 59 kDa
  • Clonality
    Polyclonal Antibody
  • Isotype
    IgG
  • Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human STK39 around the phosphorylation site of serine 325 (D-P-SP-K-R).
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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