货号： 690474
别名： NIMA-interacting protein 2, PIN2, TERF1, TRF, TTAGGG repeat binding factor 1, Telomeric protein Pin2/TRF1, Telomeric repeat binding factor 1
应用： WB
反应种属： Human,Mouse
目录价格：
RMB(含税报价)
数量： - + （库存件）
查看代理商 预计货期：3-4个工作日 说明书PDF
产品详情
  • Product Name
    Phospho-Telomeric Repeat Binding Factor 1 (Ser219) Rabbit pAb
  • Gene ID
    7013
  • SwissProt ID
    P54274
  • Gene Name
    TERF1
  • Alternative Names
    NIMA-interacting protein 2, PIN2, TERF1, TRF, TTAGGG repeat binding factor 1, Telomeric protein Pin2/TRF1, Telomeric repeat binding factor 1
  • Background
    Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
  • Research Field
    Epigenetics and Nuclear Signaling
  • Product Categories
    Primary antibody
  • Host
    Rabbit
  • Reactivity
    Human,Mouse
  • Application
    WB
  • Dilution Ratio
    WB: 1/500-1/3000
  • Molecular Weight
    Calculated MW: 50 kDa
  • Clonality
    Polyclonal Antibody
  • Isotype
    IgG
  • Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human Telomeric Repeat Binding Factor 1 around the phosphorylation site of Ser219
  • Purification
    Affinity Purified
  • Conjugation
    Unconjugated
  • Modification
    Phosphorylated
  • Form
    liquid
  • Buffer System
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
验证详情

应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定 正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。
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