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Product Name
Phospho-HIRA (Thr555) Rabbit pAb
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Gene ID
7290
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SwissProt ID
P54198
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Gene Name
HIRA
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Alternative Names
DGCR1, TUP1 like enhancer of split protein 1, TUPLE1
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Background
Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
ICC/IF
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Dilution Ratio
ICC/IF: 1/100-1/500
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Molecular Weight
Calculated MW: 111 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human HIRA around the phosphorylation site of threonine 555 (L-T-T P-P-S).
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.