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Product Name
Phospho-TNFRSF5 (Thr254) Rabbit pAb
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Gene ID
958
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SwissProt ID
P25942
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Gene Name
CD40
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Alternative Names
B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40; TNR5; tumor necrosis factor receptor superfamily member 5
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Background
Receptor for TNFSF5/CD40LG (PubMed:31331973).
Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB
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Dilution Ratio
WB: 1/500-1/3000
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Molecular Weight
Calculated MW: 30 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human TNFRSF5 around the phosphorylation site of threonine 254 (Q-E-TP-L-H)
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.