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Product Name
Phospho-ICK (Tyr159) Rabbit pAb
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Gene ID
22858
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SwissProt ID
Q9UPZ9
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Gene Name
ICK
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Alternative Names
EC 2.7.11.22; hICK; ICK; Intestinal cell kinase; KIAA0936; kinase ICK; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; MRK; Serine/threonine kinase ICK
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Background
Required for ciliogenesis (PubMed:24797473).
Phosphorylates KIF3A (By similarity).
Involved in the control of ciliary length (PubMed:24853502).
Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity).
May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity).
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/3000
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Molecular Weight
Calculated MW: 71 kDa
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Clonality
Polyclonal Antibody
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Isotype
IgG
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Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human ICK around the phosphorylation site of tyrosine 159 (T-D-YP-V-S).
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
liquid
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Buffer System
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.